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Synthesis and study of the effect of uracil and theophylline derivatives on the glucose transport into rat hepatic cells
Authors:O. N. Leonov  M. L. Tsyrenina  E. I. Melnik  V. M. Devichenskii  L. Yu. Kryukova  E. A. Vorontsov  S. L. Kuznetsov  L. N. Kryukov
Affiliation:(1) Institute of Biological Medicine, ul. Akad. Oparina 4, 117815 Moscow, Russia;(2) Center of Medical, Biological, and Ecological Problems, Russian Academy of Natural Sciences, Simferopolskii bulvar 8, 113149 Moscow, Russia
Abstract:A series of uracil and theophylline derivatives was synthesized. 4-Amino-1,3-dimethyl-5-non-anoylaminouracil displayed the most pronounced effect of thein vitro stimulation of the 2-deoxyglucose transport into hepatic rat cells. Deceased.
Keywords:glucose transport  hepatocytes  insulin  theophyllin derivatives  uracil derivatives
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