|
|||||
|
|
An EcoRI restriction fragment length polymorphism (RFLP) in the human c-erb A locus |
|
| Authors: | D. Mathieu-Mahul Qi De Xu S. Saule R. Lidereau F. Galibert R. Berger M. Mauchauffé C. J. Larsen |
| Affiliation: | (1) Laboratoire de Pharmacologie Expérimentale, U. 107 INSERM, Hôpital St Louis, Place du Dr Fournier, 75475 Paris Cédex 10, France;(2) Laboratoire d'Hematologie Expérimentale, Hôpital St Louis, Place du Dr Fournier, 75475 Paris Cédex 10, France;(3) U-186 INSERM, Institut Pasteur, 15 Rue C. Guérin, 59019 Lille Cédex, France;(4) Laboratoire de Cytogénétique, LOI CNRS, Hôpital St Louis, Place du Dr Fournier, 75475 Paris Cédex 10, France;(5) Centre anticancéreux R. Huguenin, 5 Rue G. Latouche, 92211 St Cloud, France |
| Abstract: | Summary An EcoR1 restriction fragment length polymorphism (RFLP) was detected in the 3 end of the locus of the c-erb-A proto-oncogene. The frequency of the rarer allele was around 3.0% in a normal population of 107 unrelated individuals. This frequency did not significantly differ in DNA samples from patients with breast tumors or acute leukemias. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |