Localization of temperature-sensitive transformation mutations and back mutations in the Rous sarcoma virus src gene. |
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Authors: | V J Fincham and J A Wyke |
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Abstract: | Cloning and sequencing of two temperature-sensitive transforming mutations of Rous sarcoma virus reveal that their lesions are due to distinct but close single amino acid changes near the carboxy terminus of the v-src gene product. Back mutations to wild type result from second mutations at either nearby or distant sites. |
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