The dangers of using single locus markers in parasite epidemiology: Ascaris as a case study |
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Authors: | Anderson T J |
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Institution: | Southwest Foundation for Biomedical Research, San Antonio, TX, USA. tanderso@darwin.sfbr.org |
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Abstract: | Molecular markers are used widely to discriminate between closely related species of parasites, and in many cases a single locus is used for this purpose. This article aims to show how molecular data derived from a single genetic marker or linkage group - in this case mitochondrial DNA - can lead to ambiguous conclusions and to illustrate how a multilocus approach has enhanced our understanding of the epidemiology of two closely related parasites, the nematodes Ascaris suum, which infects pigs, and Ascaris lumbicoides, which infects humans. |
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