MHC class I loci of the Bar-Headed goose (Anser indicus) |
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Authors: | Liang Qinglong Wei Lei Wang Xinwei He Hongxuan |
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Institution: | Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, National Research Center For Wildlife-Borne Diseases, Chinese Academy of Sciences, Beijing China. |
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Abstract: | MHC class I proteins mediate functions in anti-pathogen defense. MHC diversity has already been investigated by many studies in model avian species, but here we chose the bar-headed goose, a worldwide migrant bird, as a non-model avian species. Sequences from exons encoding the peptide-binding region (PBR) of MHC class I molecules were isolated from liver genomic DNA, to investigate variation in these genes. These are the first MHC class I partial sequences of the bar-headed goose to be reported. A preliminary analysis suggests the presence of at least four MHC class I genes, which share great similarity with those of the goose and duck. A phylogenetic analysis of bar-headed goose, goose and duck MHC class I sequences using the NJ method supports the idea that they all cluster within the anseriforms clade. |
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Keywords: | MHC I Anser indicus polymorphism phylogenetic analysis |
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