Viruses and RNA Interference: Issues and Controversies |
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| Authors: | Bryan R. Cullen |
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| Affiliation: | Department of Molecular Genetics & Microbiology and Center for Virology, Duke University Medical Center, Durham, North Carolina, USA |
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| Abstract: | The question of whether any mammalian cells are able to mount an effective RNA interference-mediated antiviral innate immune response has remained highly controversial. In this Gem, I review recent data addressing this important issue and propose a testable hypothesis that can explain many of the apparently contradictory results published in this area of research. |
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