A new facile chemoenzymatic synthesis of levamisole |
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| Authors: | Kamal Ahmed Khanna G B Ramesh Krishnaji T Ramu R |
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| Affiliation: | Biotransformation Laboratory, Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500007, India. ahmedkamal@iict.res.in |
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| Abstract: | An efficient and facile chemoenzymatic synthesis of levamisole by employing lipase-mediated resolution of 3-hydroxy-3-phenylpropanenitrile followed by its conversion to beta-amino alcohol as the key intermediate is described. |
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