| 基因工程抗体融合蛋白的构建 |
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| 引用本文： | 张雪洪,张惟杰.基因工程抗体融合蛋白的构建[J].中国生物工程杂志,2001,21(4):63-65. |
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| 作者姓名： | 张雪洪 张惟杰 |
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| 作者单位： | 上海交通大学生命科学技术学院 上海 200030 |
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| 摘 要： | 抗体融合蛋白可以具有抗体的特性和所融合的功能蛋白的活性,可广泛用于免疫治疗、免疫诊断、抗体纯化及抗体和抗原的分析定量等,特别可用于免疫导向药物的制备。基因工程抗体融合蛋白比传统的化学交联的抗体融合蛋白具有更多的优越性。本文就基因工程抗体融合蛋白的构建和性质做一综述 。
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| 关 键 词： | 抗体融合蛋白 抗体 基因工程 人工构建 |
Construction of Genetically Engineered Antibody Fusion Proteins |
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| Zhang Xue,hong\ Zhang Wei,jie.Construction of Genetically Engineered Antibody Fusion Proteins[J].China Biotechnology,2001,21(4):63-65. |
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| Authors: | Zhang Xue hong\ Zhang Wei jie |
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| Abstract: | Antibody fusion proteins can retain biological function of antibody and functional character of proteins fused to the antibody,can be used widely in immuno therapy,immuno diagnosis,purification of antibody and analysis of antibody or antigen.Antibody fusion protein can be particularly used to prepare the immuno directed drug.Genetically engineered antibody fusion proteins have more advantages over traditional chemical crosslinking antibody fusion proteins.Here the construction and characterization of genetically engineered antibody fusion proteins were reviewed. |
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| Keywords: | Antibody fusion protein Antibody Genetic engineering Construction |
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