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Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation
Authors:Shen Yuh-Chiang  Wang Yea-Hwey  Chou Yueh-Ching  Liou Kuo-Tong  Yen Jiin-Cherng  Wang Wen-Yen  Liao Jyh-Fei
Institution:National Research Institute of Chinese Medicine, Taipei, Taiwan;
Department of Pharmacy, Taipei Veterans General Hospital, Taiwan;
Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan;
Graduate Institute of Sport Coaching Science, Chinese Culture University, Taipei, Taiwan;
Department of Surgery Hsin-chu General Hospital, Department of Health, Hsinchu, Taiwan
Abstract:
Keywords:cerebral ischemia-reperfusion  dimemorfan  glutamate  inflammation  neuroprotection  oxidative/nitrosative stress  σ1 receptor
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