| 羌活药材活性成分的提取工艺研究 |
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| 引用本文： | 石海利,蒋舜媛,徐凯节,张艳侠,周毅,宋美凤,彭树林.羌活药材活性成分的提取工艺研究[J].天然产物研究与开发,2012,24(5):687-690,701. |
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| 作者姓名： | 石海利 蒋舜媛 徐凯节 张艳侠 周毅 宋美凤 彭树林 |
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| 作者单位： | 1. 中国科学院成都生物研究所
2. 四川省中医药科学院中药材品质与创新中药四川省重点实验室,成都,610041 |
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| 基金项目： | 科技部"重大新药创制"科技重大专项课题，四川省科技攻关项目 |
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| 摘 要： | 选择提取次数、溶剂倍数、提取时间为考察因素,以提取浸膏量及三种主要活性物质(紫花前胡苷、异欧前胡素、羌活醇)含量为考察指标,探讨羌活药材活性成分的乙醇加热回流提取工艺。在首先考察单因素对提取效果影响的基础上采用正交试验法,优选出羌活药材活性成分的最佳提取工艺参数:加6倍量95%乙醇,加热回流提取3次,每次提取时间为1 h。
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| 关 键 词： | 羌活 提取工艺 正交试验 活性成分 |
Study on Extraction Technology of Bioactive Components from Notopterygium incisum |
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| SHI Hai-li
,
JIANG Shun-yuan
,
XU Kai-jie
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ZHANG Yan-xia
,
ZHOU Yi
,
SONG Mei-feng
,
PENG Shu-lin.Study on Extraction Technology of Bioactive Components from Notopterygium incisum[J].Natural Product Research and Development,2012,24(5):687-690,701. |
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| Authors: | SHI Hai-li JIANG Shun-yuan XU Kai-jie ZHANG Yan-xia ZHOU Yi SONG Mei-feng PENG Shu-lin |
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| Institution: | 1* 1Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu 610041,China;2Sichuan Key Laboratory of Quality and Innovation Research of Chinese Materia Medica,Sichuan Academy of Chinese Medicine Sciences,Chengdu 610041,China |
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| Abstract: | To optimize the extracting procedure for Notopterygium incisum,orthogonal design was carried out.Taking the amount of solvent,times of extraction and extraction duration as the test factors and the amount of extract,nodakenin,isoimperatorin and notopterol as the test indexs,the L9(34) orthogonal design was used to optimize the extraction technology of N.incisum.The results showed that the best extraction technology was as follows:refluxing extraction with 6 times of 95% alcohol for 3 times(1 h each time). |
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| Keywords: | Notopterygium incisum extracting procedure orthogonal array design bioactive component |
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