Segmental pulmonary vascular responses to ATP in rat lungs: role of nitric oxide |
| |
Authors: | Hakim, Tawfic S. Ferrario, Lara Freedman, Jeffrey C. Carlin, Robert E. Camporesi, Enrico M. |
| |
Abstract: | Hakim, Tawfic S., Lara Ferrario, Jeffrey C. Freedman, RobertE. Carlin, and Enrico M. Camporesi. Segmental pulmonary vascularresponses to ATP in rat lungs: role of nitric oxide. J. Appl. Physiol. 82(3): 852-858, 1997.ATP exhibits vascular pressor and depressor responses in a dose-and tone-dependent manner. The vascular site of ATP-induced contractionor dilation has not previously been characterized. Using the vascularocclusion technique, we investigated the effects of ATP in isolated rat lungs perfused with autologous blood (hematocrit = 20%) and described its action during resting and elevated tone in terms of changes inresistances of the small and large arteries and veins. During restingtone, ATP (105M) |
| |
Keywords: | |
|
| 点击此处可从《Journal of applied physiology》浏览原始摘要信息 |
|
点击此处可从《Journal of applied physiology》下载全文 |
|