Simulation of thermoregulation in serotonin-depleted rats subjected to acceleration fields |
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Affiliation: | Department of Animal Physiology, University of California, Davis, CA 95616, USA |
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Abstract: | A computer simulation of thermoregulation in mammals during and following exposure to hypergravitational fields is developed. This simulation includes the effects of a neurotransmitter, serotonin, and the initial transients of the system when the animal is first placed in a hypergravitational field. Experimental data on the response of rats to serotonin depletion helps place the site at which serotonin acts in the model. |
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