Strictly polyphosphate-dependent glucokinase in a polyphosphate-accumulating bacterium,Microlunatus phosphovorus |
| |
| Authors: | Tanaka Shotaro Lee Sun-Og Hamaoka Kazuhiro Kato Junichi Takiguchi Noboru Nakamura Kazunori Ohtake Hisao Kuroda Akio |
| |
| Affiliation: | Department of Molecular Biotechnology, Hiroshima University, Hiroshima 739-8530, Japan. |
| |
| Abstract: | ATP-dependent glucokinase is suggested to have evolved from a hypothetical polyphosphate (polyP)-dependent glucokinase (polyP-GK) via a bifunctional polyP/ATP glucokinase (polyP/ATP-GK). Here we showed that polyP-GK is present in a polyP-accumulating bacterium, Microlunatus phosphovorus. The polyP-GK produced glucose-6-P(i) from glucose and polyP, but it could not phosphorylate glucose with ATP. The polyP-GK was most closely related to the polyP/ATP-GK of Mycobacterium tuberculosis. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
