Screening of a High Growth Influenza B Virus Strain in Vero Cells |
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| Authors: | Ze LIU Wei-dong LI Ming-bo SUN Lei MA Zi-quan GUO Shu-de JIANG Guo-yang LIAO Jing-si YANG Chang-gui LI |
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| Affiliation: | Ze LIU 1,Wei-dong LI 1,Ming-bo SUN 1,Lei MA 1,Zi-quan,GUO 1,Shu-de JIANG 1,Guo-yang LIAO 1,Jing-si YANG 1** , Chang-gui LI 2** (1.Institute of Medical Biology,Chinese Academy of Medical Sciences,Kunming 650118,China,2.National Institute for the Control of Pharmaceutical , Biological Products,Beijing 100050,China) |
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| Abstract: | Due to the insufficient supply of embryonated chicken eggs,the preparation of large quantities of inactivated influenza vaccines will require an alternative virus culture system after the emergence or reemergence of a pandemic influenza virus.The Vero cell is one of the ideal options since it was used for producing many kinds of human vaccines.However,most of the influenza viruses can not grow well in Vero cells.To develop a new influenza vaccine with Vero cells as a substrate,the virus needs to adapt to th... |
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| Keywords: | Influenza B Virus Vero Cells Adaption |
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