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Application of lipase catalysis in organic solvents for selective protection–deprotection of bioactive compounds
Authors:Daniela Lambusta   Giovanni Nicolosi   Angela Patti  Claudia Sanfilippo
Affiliation:

CNR Istituto Chimica Biomolecolare, Sezione di Catania, Via del Santuario 110, 95028, Valverde CT, Italy

Abstract:Lipases are useful catalysts to realise in non-conventional medium esterifications and alcoholysis of polyhydroxylated compounds with high level of regioselectivity. This paper describes some examples of regioprotection–deprotection of flavonoids and conduritols, realised in our laboratory, using Pseudomonas cepacia, Mucor miehei and Candida cylindracea (C. rugosa) lipases.
Keywords:Lipase   Flavonoid   Conduritol   Biocatalysis
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