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Application of human umbilical cord blood-derived mesenchymal stem cells in disease models
Authors:Kim Ju-Yeon  Jeon Hong Bae  Yang Yoon Sun  Oh Wonil  Chang Jong Wook
Institution:Ju-Yeon Kim, Hong Bae Jeon, Yoon Sun Yang, Wonil Oh, Jong Wook Chang, Biomedical Research Institute, MEDIPOST Co., Ltd, Seoul 137-874, South Korea.
Abstract:Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) are regarded as an alternative source of bone marrow-derived mesenchymal stem cells because collection of cord blood is less invasive than that of bone marrow. hUCB-MSCs have recently been studied for evaluation of their potential as a source of cell therapy. In this review, the general characteristics of hUCB-MSCs and their therapeutic effects on various diseases in vitro and in vivo will be discussed.
Keywords:Regeneration  Immune modulation  Nursing effect  Mesenchymal stem cells
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