Vitamin K-dependent carboxylation of poly-L-glutamate. |
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Authors: | B A Soute R Budé C Vermeer |
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Institution: | Department of Biochemistry, University of Limburg, Maastricht The Netherlands. |
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Abstract: | Poly-L-glutamate preparations of varying chain length were used as substrates for bovine liver vitamin K-dependent carboxylase. The quality of these substrates (as measured by their apparent kinetic constants) was comparable to that of the more commonly used tri- and pentapeptides, but the maximal reaction rate increased at increasing chain length. |
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