Characterization of two different toxins of Wickerhamomyces anomalus (Pichia anomala) VKM Y-159 |
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| Authors: | Farkas Z Márki-Zay J Kucsera Judit Vágvölgyi Cs Golubev W I Pfeiffer Ilona |
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| Institution: | Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary. |
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| Abstract: | Wickerhamomyces anomalus VKM Y-159 strain produces two types of toxin designated as WAKT a and WAKT b, encoded by chromosomal genes. The WAKT a toxin is heat-labile, pronase sensitive acting in pH range 3-4 affecting on several yeasts including pathogenic Candida species while the WAKT b toxin is protease- and thermo-resistant, acting in pH range 3-7 on two species, Candida alai and Candida norvegica. The rapid decrease of the number of viable cells after toxin treatment demonstrates that both toxins have cytocidic effect. |
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