Content of endogenous opiates and adrenocorticotropic hormone in the brain structures of rats of different ages |
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Authors: | A. N. Voloshin I. A. Komarevtseva |
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Affiliation: | (1) Lugansk State Medical University, Ministry of Public Health of Ukraine, Ukraine |
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Abstract: | The contents of beta-endorphin (BE), methionine-enkephalin (MEK), and adrenocorticotropic hormone (ACTH) in the hypophysis and hypothalamus of intact 4- to 6-week-old and 16-week-old Wistar rats was studied. The maximum BE concentration was found in the hypophysis, whereas the maximum MEK and ACTH concentrations were found in the hypothalamus. Aging was followed by a decrease in the concentrations of all above substances, except BE, whose concentration in the hypophysis of the older rat group was markedly higher than in the hypophysis of 4- to 6-week-old animals. |
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