Molecular docking analysis of human JAK2 with compounds from tomatoes |
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| Authors: | Umapathy Vidhya Rekha M Anita S Bhuminathan K Sadhana |
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| Institution: | 1.Department of Public Health Dentistry, Sree Balaji Dental College and Hospital, Pallikaranai, Chennai 600 100, India;2.Department of Prosthodontics, Sree Balaji Dental College and Hospital, BIHER, Pallikaranai, Chennai 600 100, India |
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| Abstract: | Janus kinase 2 (JAK2) is a tyrosine kinase receptor that belongs to the JAK family kinases is linked to oral cancer. We describe the molecular binding analysis of JAK2 with 23 compounds from tomotoes. Docking data shows five compounds (rutin, qucertin, narigenin, chlrogenia acid & kaempferol) with optimal binding features with JAK2 for further consideration. |
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| Keywords: | Lycopersicon esculentum JAK2 Oral Cancer Molecular docking |
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