The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. |
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Authors: | P Chavrier K Simons M Zerial |
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Institution: | Cell Biology Programme, European Molecular Biology Laboratory, Heidelberg, F.R.G. |
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Abstract: | Partial sequences corresponding to eleven novel Rab proteins and one new Rho protein have been isolated using a PCR-based cloning approach. These results confirm that the overall diversity of the Rab and Rho protein subfamilies account for more than thirty different members in mammalian cells. |
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