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The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach.
Authors:P Chavrier  K Simons  M Zerial
Institution:Cell Biology Programme, European Molecular Biology Laboratory, Heidelberg, F.R.G.
Abstract:Partial sequences corresponding to eleven novel Rab proteins and one new Rho protein have been isolated using a PCR-based cloning approach. These results confirm that the overall diversity of the Rab and Rho protein subfamilies account for more than thirty different members in mammalian cells.
Keywords:
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