Chromosomal assignment of the human smg GDP dissociation stimulator gene to human chromosome 4q21-q25 |
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| Authors: | Olaf Riess Cornelia Epplen Ina Siedlaczck Jörg T. Epplen |
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| Affiliation: | (1) Abteilung für Molekulare Humangenetik, Ruhr Universität, Universitätsstrasse 150, D-44780 Bochum, Germany |
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| Abstract: | The 3 -end of the cDNA encoding the smg GDP dissociation stimulator (smg GDS) protein shares 100% homology with the previously published expressed sequence tag 00038 site. This site extends the 3-end of the smg GDS gene by 212 bp. It has been localized to human chromosome 4. Here, we have refined the localization of smg GDP to human chromosome 4q21-q25 using a mapping panel of rodent/human somatic cell hybrids containing different parts of chromosome 4. This chromosomal localization of smg GDP to 4q21-25 overlaps with a region of allele loss in primary hepatocellular carcinoma (4q13-q26).HGM symbol: RAP1GDS1 |
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