CELL KINETICS OF A CHONDROSARCOMA |
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Authors: | Anne Dawson N F Kember |
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Institution: | Physics Department, St Bartholomew's Hospital Medical College, London |
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Abstract: | The cell kinetics of the transplantable DC-II mouse chondrosarcoma have been studied by the pulse labelled mitoses method. The analysis gave the following estimates for the phases of the cell cycle: G, 10-5 hr; S, 9-5 hr; G2, 4 hr with an intermitotic time of 23-5 hr. Consideration of the overall growth of the tumour indicated that the growth fraction and cell loss factor both had values of about 0–5. The results are compared with cell kinetic data from sarcomas and other cartilage tissues. |
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