Institut de Physique des Systèmes Biologiques, Laboratory of Structural Biology and Biophysics, Ecole Polytechnique Fédérale de Lausanne (EPFL), BSP-415, CH-1015, Lausanne, Switzerland.
Abstract:
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Highlights? Phage tails and other contractile injection systems contain a central spike protein ? The tip of the spike is “hardened” by a centrally positioned iron ion ? The spike appears to pierce the host cell membrane without unfolding ? An OB-fold with an extra β-hairpin is a conserved feature of all central spikes
