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Antioxidant activity of Arthritin--a polyherbal formulation
Authors:Chamundeeswari D  Vaijayanthi V  Umamaheswari S  Gandhimathi C  Karna S L Rajasekar  Meignanam E  Vasantha J
Institution:Sri Ramachandra College of Pharmacy, Sri Ramachandra Medical College and Research Institute (Deemed University), Porur, Chennai 600 116, India.
Abstract:In complete freund's adjuvant induced arthritis in male albino rats, a significant increase in serum lipid peroxidase besides increase in paw swelling and a significant decrease in superoxide dismutase, glutathione peroxidase and total reduced glutathione levels were observed. Arthritin produced a marked reversal of these enzyme levels, besides a significant reduction in paw swelling. The results suggest that, the polyherbal formulation 'Arthritin' exerts its effects by modulating lipid peroxidation and enhancing anti-oxidant and detoxifying enzyme systems.
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