Functional organization of calcium stores in polarized secretory cells and transcellular calcium transport |
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Authors: | A V Tepikin O H Petersen |
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Institution: | (1) University of Liverpool, Liverpool, Great Britain |
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Abstract: | In this short review, we will first discuss localized cytoplasmic calcium signals in pancreatic acinar cells. In the second
part of the review, we will describe recently discovered polarized calcium efflux and calcium propagation through the lumen
of the endoplasmic reticulum — ER (a phenomenon we have termed “calcium tunnelling”). Finally, we will present a hypothesis
concerning the roles that these mechanisms could play in transcellular calcium flux. |
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Keywords: | |
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