Switching and signaling at the telomere |
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| Authors: | Blackburn E H |
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| Institution: | Department of Biochemistry and Biophysics, University of California, San Francisco, 94143, USA. telomer@itsa.ucsf.edu |
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| Abstract: | This review describes the structure of telomeres, the protective DNA-protein complexes at eukaryotic chromosomal ends, and several molecular mechanisms involved in telomere functions. Also discussed are cellular responses to compromising the functions of telomeres and of telomerase, which synthesizes telomeric DNA. |
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