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基因打靶技术在人类疾病动物模型研究中的应用
引用本文:袁进,顾为望. 基因打靶技术在人类疾病动物模型研究中的应用[J]. 中国实验动物学杂志, 2008, 0(1): 58-62
作者姓名:袁进  顾为望
作者单位:南方医科大学实验动物中心,广州510515
摘    要:人类疾病动物模型在医学研究中起着非常重要的作用,而自然发生的人类疾病已远远不能满足医学研究的需要。利用基因打靶技术开展人类疾病动物模型的研究具有广阔的应用前景。本文就基因打靶技术及其在人类疾病动物模型研究中的应用做一介绍。

关 键 词:基因打靶  人类疾病动物模型

Applications of Gene Targeting in Animal Model of Human Disease
YUAN Jin,GU Wei-wang. Applications of Gene Targeting in Animal Model of Human Disease[J]. Chinese Journal of Laboratory Animal Science, 2008, 0(1): 58-62
Authors:YUAN Jin  GU Wei-wang
Affiliation:(Laboratory Animal Center of Southern Medical University, Guangzhou 510515, China)
Abstract:Animal model of human disease plays an important role in medical research, but spontaneous human disease cannot satisfy needs of medical research. Thus, it has wide applied prospect that research of animal model of human disease is performed by using gene targeting. Gene targeting technology and its application in research of animal model of human disease were briefed in this paper.
Keywords:Gene targeting   Animal model of human disease
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