Diversion of cytoskeletal processes by Shigella during invasion of epithelial cells |
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| Authors: | Bourdet-Sicard R Egile C Sansonetti P J Tran Van Nhieu G |
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| Affiliation: | Unité de pathogénie microbienne moléculaire, Inserm U389, Institut Pasteur, Paris, France. |
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| Abstract: | Shigella, the causative agent of bacillar dysentery, invades colonic epithelial cells and moves intracellularly to spread from cell to cell. The processes of Shigella entry, determined by the Ipa proteins, and of actin-based motility, dependent on the IcsA/VirG protein, represent different levels of bacterial manipulation of the cell cytoskeleton. |
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