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Structural Basis of MRG15-Mediated Activation of the ASH1L Histone Methyltransferase by Releasing an Autoinhibitory Loop
Authors:Yoonjung Lee  Eojin Yoon  Saehyun Cho  Sigrun Schmähling  Jürg Müller  Ji-Joon Song
Affiliation:1. Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Korea;2. Center for Bioanalysis, Korea Research Institute of Standards and Science, 267 Gajeong-ro, Yuseong-gu, Daejeon 34113, Korea;3. MPI of Biochemistry, Laboratory of Chromatin Biology, Am Klopferspitz 18, 82152 Martinsried, Germany
Abstract:
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  • Keywords:chromatin  nucleosome  complex  activation  autoinhibition  regulation  structure  X-ray crystallography
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