| 着丝粒结构与功能研究的新进展 |
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| 引用本文： | 丁戈,姚南,吴琼,刘恒,郑国锠. 着丝粒结构与功能研究的新进展[J]. 植物学通报, 2008, 25(2): 149-160 |
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| 作者姓名： | 丁戈 姚南 吴琼 刘恒 郑国锠 |
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| 作者单位： | 1. 兰州大学生命科学学院细胞生物学研究所,,兰州,730000
2. 兰州大学第一医院,兰州,730000 |
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| 摘 要： | 着丝粒是真核生物染色体的显著特征。在细胞有丝分裂和减数分裂中，着丝粒作为保证染色体正常分裂并分离到子细胞的结构和功能元件，参与了同源染色体配对、姐妹染色单体黏合、分离及分裂后期启动的调控等。本文对近年来着丝粒结构和功能研究的新进展进行了概述。
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| 关 键 词： | 着丝粒 表观遗传学 RNA干扰 |
| 修稿时间： | 2007-08-14 |
Research Progress on the Structure and Function of Centromeres |
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| Ge Ding,Nan Yao,Qiong Wu,Heng Liu,Guochang Zheng. Research Progress on the Structure and Function of Centromeres[J]. Chinese Bulletin of Botany, 2008, 25(2): 149-160 |
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| Authors: | Ge Ding Nan Yao Qiong Wu Heng Liu Guochang Zheng |
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| Affiliation: | Ge Ding, Nan Yao, Qiong Wu, Heng Liu, Guochang Zheng( 1 Institute of Cell Biology, College of Life Science, Lanzhou University, Lanzhou 730000, China 2 First Hospital, Lanzhou University, Lanzhou 730000, China) |
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| Abstract: | As the remarkable characteristic of every eukaryotic chromosome, the centromere is the structural and functional element that ensures the normal split and separation of chromosomes during mitosis and meiosis. It is involved in processes such as homologous chromosome pairing, sister chromatid adhesion and separation, and some of the regulation initiated during anaphase. Here we review some of recent progress in research into the structure and function of centromeres. |
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| Keywords: | centromere epigenetics RNAi |
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