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miRAS: a data processing system for miRNA expression profiling study |
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| Authors: | Feng Tian Huayue Zhang Xinyu Zhang Chi Song Yongjing Xia Yiqing Wu Xiangjun Liu |
| Affiliation: | (1) Department of Biological Science and Biotechnology, Tsinghua University, Beijing, 100084, People's Republic of China;(2) Institutes of Biomedicine, Tsinghua University, Beijing, 100084, People's Republic of China;(3) Ministry of Education Key Laboratory of Bioinformatics, Tsinghua University, Beijing, 100084, People's Republic of China |
| Abstract: | BackgroundThe study of microRNAs (miRNAs) is attracting great considerations. Recent studies revealed that miRNAs play as important regulators of gene expression and some even as cancer players or inhibitors. Many studies try to discover new miRNAs and reveal the miRNA expression profile in cancer using a SAGE-based total RNA clone method. However, the data processing of this method is labor-intensive with several different biological databases and more than ten data processing steps involved. |
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