Ligands specify estrogen receptor alpha nuclear localization and degradation |
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| Authors: | Silvia Kocanova Mahta Mazaheri Stéphanie Caze-Subra Kerstin Bystricky |
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| Affiliation: | 1.Laboratoire de Biologie Moléculaire Eucaryote,Université de Toulouse; UPS,Toulouse,France;2.CNRS; LBME,Toulouse,France |
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| Abstract: | Background The estrogen receptor alpha (ERα) is found predominately in the nucleus, both in hormone stimulated and untreated cells. Intracellular distribution of the ERα changes in the presence of agonists but the impact of different antiestrogens on the fate of ERα is a matter of debate. |
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