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Iridoid glucosides from Viburnum tinus
Affiliation:1. Department of FSTC Clinic of the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China;2. Department of Internal Medicine of Traditional Chinese Medicine, Huzhou Central Hospital, Huzhou 310003, China;3. Department of Internal Medicine of Traditional Chinese Medicine, Zhejiang Hospital, Hangzhou 310007, China;4. Department of Pediatrics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China;1. Programa de Doctorado del Departamento de Ciencias Biológicas y de la Salud, UAM-I, Universidad Autónoma Metropolitana Campus Iztapalapa, Ciudad de México, Mexico;2. Unidad de Investigación Médica en Enfermedades Neurológicas, Hospital de Especialidades, “Dr. Bernardo Sepúlveda”, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, IMSS, Ciudad de México, Mexico;3. Departamento de Farmacobiología, Centro de Investigación y Estudios Avanzados, Tlalpan, Ciudad de México, Mexico;4. División de Investigación en Neurociencias, Instituto Nacional de Psiquiatría “Ramón de la Fuente Muñis”, Ciudad de México, Mexico;5. Área de Neurociencias. Departamento de Neurohistología y Conducta. Departamento de Biología de la Reproducción, Universidad Autónoma Metropolitana-Iztapalapa, Ciudad de México, Mexico;1. Biotechnology Group, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran;2. Chemical Engineering Department, Faculty of Engineering, University of Sistan and Baluchestan, Zahedan, Iran;1. School of life sciences, Jilin University, Changchun 130012, China;2. School of Chinese Medicine, LKS Faculty of Medicine, the University of Hong Kong, Hong Kong, China
Abstract:Five new iridoid glucosides, named viburtinosides I-V, together with suspensolide F, were isolated from leaves and branches of Viburnum tinus. All the iridoids contain a β-d-glucopyranosyl moiety linked to the oxymethylene at C-11 and an isovaleroyl at position 1, but differ for other acylating groups. The structures have been elucidated mainly by spectroscopic means.
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