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Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis
Authors:Joseph C Genereux  Song Qu  Minghai Zhou  Lisa M Ryno  Shiyu Wang  Matthew D Shoulders  Randal J Kaufman  Corinne I Lasmézas  Jeffery W Kelly  R Luke Wiseman
Affiliation:1. Department of Infectious Diseases, The Scripps Research Institute, Jupiter, FL, USA;2. Department of Molecular & Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA;3. Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA;4. Degenerative Disease Research Program, Sanford Burnham Medical Research Institute, La Jolla, CA, USA;5. The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA;6. Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA
Abstract:
Keywords:ER stress   ERdj3   extracellular proteostasis   molecular chaperones   unfolded protein response
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