| 绿茶抗氧化剂成分抑制突变作用的初步研究 |
| |
| 引用本文： | 程书钧,何其傥,罗焕造,包永德,蒋原宙,李铭新,高燕宁,主歌风,白瑾峰,郭素萍,李秀琴.绿茶抗氧化剂成分抑制突变作用的初步研究[J].分子细胞生物学报,1986(4). |
| |
| 作者姓名： | 程书钧 何其傥 罗焕造 包永德 蒋原宙 李铭新 高燕宁 主歌风 白瑾峰 郭素萍 李秀琴 |
| |
| 作者单位： | 中国医学科学院肿瘤研究所
(程书钧，罗焕造，蒋原宙，李铭新，高燕宁，主歌风，白瑾峰，郭素萍)，美国新泽西Rutgers大学食品科学系
(何其傥，包永德)，中国医学科学院肿瘤研究所(李秀琴) |
| |
| 基金项目： | 中国科学院科学基金资助 |
| |
| 摘 要： | 绿茶水溶性提取物及茶叶中抗氧化剂成份具有明显的抑制AFB_1及Bap诱导的鼠伤寒沙门氏菌回复突变作用。这种抗氧化剂成份还可以抑制AFB_1和Bap诱导的V79细胞基因正向突变,以及AFB_1诱导的V79细胞SCE和染色体畸变。本实验结果提示,绿茶中抗氧化剂成份可能对AFB_1及Bap的致癌性具有抑制作用。本文就茶叶抗氧化剂抑制突变的可能机制进行了初步讨论。
|
A PRELIMINARY STUDY ON THE ANTIMUTAGENICITY OF GREEN TEA ANTIOXIDANTS |
| |
| Cheng Shu-jun,Ho Chi-tang,Lou Huan-zao,Bao Yong-de,Jian Yuan-zhou,Li Min-hsin,Gao Yan-ning,Zhu Ge-feng,Bai Jin-feng,Guo Su-ping,and Li Xiu-qin.A PRELIMINARY STUDY ON THE ANTIMUTAGENICITY OF GREEN TEA ANTIOXIDANTS[J].Journal of Molecular Cell Biology,1986(4). |
| |
| Authors: | Cheng Shu-jun Ho Chi-tang Lou Huan-zao Bao Yong-de Jian Yuan-zhou Li Min-hsin Gao Yan-ning Zhu Ge-feng Bai Jin-feng Guo Su-ping and Li Xiu-qin |
| |
| Abstract: | The water extract of green tea,andthe antioxidants(Fraction 6)isolatedfrom green tea showed a strong inhibi-tion on the backward mutation inducedby aflatoxin B,(AFB,)and benzo(a)pyrene(BaP)in Salmonella typhimurium.The tea antioxidants inhibited gene for-ward mutation in V 79 cells treated withAFB_1 and BaP,and also decreased thefrequency of sister chromatid exchangesand chromosome aberrations in V 79 cellstreated with AFB_1. The experimental results indicatedthat the tea antioxidants probably inhi-bit the carcinogenicity of AFB_1 and Bap.The possible mechanisms of the inhibi-tion of mutagenicity by the tea antioxi-dants were discussed. |
| |
| Keywords: | Desmutagen Tea antioxidants |
| 本文献已被 CNKI 等数据库收录！ |
|
