Recent insertion of an alu sequence in the beta-globin gene cluster of the gorilla |
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Authors: | G. Trabuchet Y. Chebloune P. Savatier J. Lachuer C. Faure G. Verdier V. M. Nigon |
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Affiliation: | Département de Biologie Générale et Appliquée Claude Bernard-Lyon, Villeurbanne, France. |
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Abstract: | We present the nucleotide sequence of a new Alu family member that lies between the delta- and beta-globin genes in gorilla DNA. The sequence exhibits 91% similarity with a consensus sequence of the Alu family. It is flanked by a perfect repetition of a 16-nucleotide target sequence and terminates with 24 adenylic residues. As this sequence is absent at this locus in other primate DNAs, its insertion occurred less than 8 million years ago, thus supporting the idea that Alu sequences are still mobile elements in the hominoid genome. |
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