| 海南文昌清澜港红树林真菌抗B16肿瘤细胞活性菌株的筛选 |
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| 引用本文： | 缪承杜,庄令,林海鹏,洪葵.海南文昌清澜港红树林真菌抗B16肿瘤细胞活性菌株的筛选[J].微生物学报,2008,24(6):975-979. |
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| 作者姓名： | 缪承杜 庄令 林海鹏 洪葵 |
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| 作者单位： | 中国热带农业科学院热带生物技术研究所, 海口 571101; 海南大学农学院, 儋州 571737;中国热带农业科学院热带生物技术研究所, 海口 571101;中国热带农业科学院热带生物技术研究所, 海口 571101;中国热带农业科学院热带生物技术研究所, 海口 571101 |
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| 基金项目： | 科技部社会公益项目(No. 2004DIB3J072)资助。 |
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| 摘 要： | 从海南文昌清澜港红树林采集78份植物组织和土壤样品。对样品进行真菌分离, 共分离得到真菌608株, 采用目测法对其体外抗肿瘤细胞活性进行检测, 发现81株红树林真菌对小鼠黑色素瘤B16细胞有不同程度的抑制作用, 占总分离菌株的13.32%。结果表明, 从红树植物杯萼海桑中分离得到真菌菌株的数量最多, 而从红树植物银叶树分离得到的抗肿瘤细胞活性菌株数量最多。
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| 关 键 词： | 红树林 真菌 分离 抗B16肿瘤细胞活性 |
Screening of Cytotoxic Activity Against B16 Tumor Cell of Mangrove Fungi Isolate from Qinglan Harbor in Hainan |
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| Chengdu Miao,Ling Zhuang,Haipeng Lin and Kui Hong.Screening of Cytotoxic Activity Against B16 Tumor Cell of Mangrove Fungi Isolate from Qinglan Harbor in Hainan[J].Acta Microbiologica Sinica,2008,24(6):975-979. |
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| Authors: | Chengdu Miao Ling Zhuang Haipeng Lin and Kui Hong |
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| Institution: | The Institute of Tropical Bioscience and Biotechnology, Haikou 571101, China; Agricultural College, Hainan University, Danzhou 571737, China;The Institute of Tropical Bioscience and Biotechnology, Haikou 571101, China;The Institute of Tropical Bioscience and Biotechnology, Haikou 571101, China;The Institute of Tropical Bioscience and Biotechnology, Haikou 571101, China |
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| Abstract: | Six hundred and eight fungi strains were isolated from seventy-eight samples of mangrove plants and soil that collected from Qinglan harbor. Cyctotoxic activity was detected by observing the growth inhibition or killing of the tumor cells under microscope. The result showed that 81 strains (about 13.32% of the total strains isolated) displayed cytotoxic activity against B16 tumor cell. The most fungi strains were isolated from mangrove plant Sonneratia alba, and most of cytotoxic active fungi strains were isolated from mangrove plant Heritiera littoralis. |
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| Keywords: | mangrove fungi isolate cytotoxicity against B16 tumor cell |
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