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Distributed current analyses of bi-hemispheric magnetic N1m responses to ipsi/contralateral monaural stimuli from a single subject
Institution:1. The Open University, Department of Physics, Milton Keynes MK7 6AA UK;2. Department of Exp. Neuropsychiatry, kpfklinik, Schwabachalage 6, W-8520 Erlangen Germany;1. Department of Physiology, Faculty of Science, Mahidol University, Ratchathewi, Bangkok 10400, Thailand;2. Department of Anatomy, Faculty of Science, Mahidol University, Ratchathewi, Bangkok 10400, Thailand;3. Department of Biochemistry, Faculty of Science, Chulalongkorn University, Phyathai, Bangkok 10330, Thailand;4. Excellent Center for Drug Discovery (ECDD), Thailand Center of Excellence for Life Sciences (TCELS), Bangkok 10400, Thailand;5. Center of Excellence on Medical Biotechnology, Ministry of Education, Bangkok 10400, Thailand;1. Department of Economics, Chung-Ang University, Seoul, South Korea;2. Department of International Logistics, Chung-Ang University, Seoul, South Korea;3. School of Civil and Environmental Engineering, Nanyang Technological University, Singapore;1. State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, China;2. National Research and Development Center for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China;3. Sichuan Sundaily Farm Ecological Food Co., Ltd., Mianyang 621010, China;4. Sichuan Tieqilishi Industrial Co., Ltd., Mianyang 621010, China;5. Graduate School of Agricultural and Life Sciences, The University of Tokyo, Ibaraki 319-0206, Japan;1. Key Laboratory of State Forestry Administration on Tropical Forestry Research, Research Institute of Tropical Forestry, Chinese Academy of Forestry, Guangzhou 510520, China;2. Urban Forest Research Center, State Forestry Administration/Key Laboratory of Forest Silviculture of State Forestry Administration, Research Institute of Forestry, Chinese Academy of Forestry, Beijing 100091, China;3. South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China;1. University of Milano, 20126 Milano, Italy;2. University of Bergamo, 24044 Dalmine (BG), Italy
Abstract:Magnetoencephalographic (MEG) responses of both auditory cortices to simple auditory stimuli presented monaurally to either ear were recorded from a single subject. A distributed current model and a current dipole model were used to analyse the responses at the latency of the dominant N1m complex. At the N1m the current density was localised to a single area and was consequently well modelled by a single current dipole close to the peak current density. In the left hemisphere, the contralateral response (as identified by the peak current density) preceded the ipsilateral response by 3 msec. This value was 7 msec for the right hemisphere. Evidence was found in the right hemisphere of a posterior-anterior movement along the sylvian fissure. Also, the left hemisphere N1m sources were all represented more posterior than the right hemisphere N1m sources.
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