Elevated urinary excretion of endothelins in streptozotocin diabetic rats |
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Affiliation: | Department of Pharmacology at R & D of Sigma-Tau S.p.A., Via Pontina Km. 30.400, 00040 Pomezia, Roma, Italy |
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Abstract: | Endothelin-1,2 urinary excretion, has been determined in control and streptozotocin diabetic rats at different times after diabetes induction. Diabetic rats showed increased urinary excretion of endothelins as compared to control rats, already three days after diabetes induction and up to 20 weeks. |
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