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血虚证动物模型的标准化研究初探
引用本文:杨岚,祝彼得,彭成.血虚证动物模型的标准化研究初探[J].四川动物,2006,25(1):160-164.
作者姓名:杨岚  祝彼得  彭成
作者单位:1. 成都中医药大学解剖组胚教研室,成都610072
2. 成都中医药大学
3. 成都中医药大学科技处
基金项目:四川省科技厅资助项目;成都中医药大学校科研和教改项目
摘    要:目的:建立标准化的血虚证动物模型。方法:采用慢性失血法、溶血法和骨髓抑制法制造三种血虚证模型,观察一般情况和与血发生有关的实验室指标,并用四物汤反证造摸效果。结果:三种动物模型均符合血虚证表现,同时出现外周血、骨髓有核细胞数目和细胞周期的改变,四物汤对3种动物模型均有一定疗效。结论:建立了3种符合标准化的血虚证模型。

关 键 词:血虚证  动物模型  实验研究
文章编号:1000-7083(2006)01-0160-05
收稿时间:2005-08-25
修稿时间:2005年8月25日

Study on Standard Animal Models with Blood Deficiency Sign
YANG Lan,ZHU Bi-de,PENG Cheng.Study on Standard Animal Models with Blood Deficiency Sign[J].Sichuan Journal of Zoology,2006,25(1):160-164.
Authors:YANG Lan  ZHU Bi-de  PENG Cheng
Institution:Chengdu University of Traditional Chinese Medicine, Chengdu 610072
Abstract:Objective To establish standard animal models with blood deficiency sign.Method Three kinds of blood deficiency animal models were estabished by chronic blood loss,hemolysis and arrest of bone marrow respectively.The changes of body sign and laboratory indices were observed.Then the curative effect of Siwu Tang(Decoction of Four Ingredients)was examined as an evidence.Result Blood deficiency signs occurred in all three kinds of animal models and they had changes in periferal blood,bone marrow nucleated cells and cell cycle.Besides,Siwu Tang revealed good curative effect of these changes.Conclusion Three kinds of standard animal modles with blood deficiency sign were established.
Keywords:blood deficiency sign  animal modle  study
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