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Steroidogenic acute regulatory protein/aldosterone synthase mediates angiotensin II-induced cardiac fibrosis and hypertrophy |
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| Authors: | Zhang Wei-Wei Zheng Rong-Hua Bai Feng Sturdivant Katelyn Wang Ning-Ping James Erskine A Bose Himangshu S Zhao Zhi-Qing |
| Institution: | 1.Department of Basic Biomedical Sciences, Mercer University School of Medicine, Savannah, GA, USA ;2.Department of Physiology, Shanxi Medical University, Taiyuan, Shanxi, China ;3.Department of Internal Medicine, Navicent Health, Macon, GA, USA ;4.Cardiovascular Research Laboratory, Mercer University School of Medicine, 1250 East 66th Street, Savannah, GA, 31404, USA ;5.Department of Anesthesiology, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, China ; |
| Abstract: | Molecular Biology Reports - Aldosterone produced in adrenal glands by angiotensin II (Ang II) is known to elicit myocardial fibrosis and hypertrophy. This study was designed to test the hypothesis... |
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