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Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells |
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| Authors: | Odagiri Naoshi Matsubara Tsutomu Higuchi Moe Takada Sayuri Urushima Hayato Sato-Matsubara Misako Teranishi Yuga Yoshizato Katsutoshi Kawada Norifumi Ikeda Kazuo |
| Institution: | 1.Department of Anatomy and Regenerative Biology, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan ;2.Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan ;3.Endowed Laboratory of Synthetic Biology, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan ;4.Academic Advisor’s Office of PhoenixBio Co. Ltd, Higashihiroshima, 739-0046, Japan ; |
| Abstract: | Molecular and Cellular Biochemistry - Senescent hepatic stellate cells (senescent HSCs) are found in patients with liver cirrhosis and have been thought to be involved in the development of... |
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