Methinin: A peptide inhibitor of methylation |
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| Authors: | Ellen Sue Lyon Peter McPhie William B. Jakoby |
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| Affiliation: | Section on Enzymes and Cellular Biochemistry, NIADDK, National Institutes of Health, Bethesda MD 20205 USA |
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| Abstract: | Five enzymes, active in the transfer of a methyl group to either oxygen, nitrogen or sulfur atoms, were inhibited competitively by a peptide isolated from rabbit liver. The peptide, named methinin, appears to have a chromophore that resembles pyridinoline, a cross linking amino acid found in elastin and collagen. |
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