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Complete Genome Sequences of Two Helicobacter pylori Bacteriophages Isolated from Japanese Patients
Authors:Jumpei Uchiyama  Hiroaki Takeuchi  Shin-ichiro Kato  Iyo Takemura-Uchiyama  Takako Ujihara  Masanori Daibata  Shigenobu Matsuzaki
Institution:aDepartment of Microbiology and Infection;bCenter for Innovative and Translational Medicine;cDepartment of Clinical Laboratory Medicine, Faculty of Medicine;dResearch Institute of Molecular Genetics;eScience Research Center, Kochi University, Kochi, Japan
Abstract:Helicobacter pylori causes peptic ulcers and gastric cancer, which lead to significantly higher morbidity in Japan than elsewhere in the world. As bacteriophage (phage) and host bacteria coevolve, the study of H. pylori phages is important to extend understanding of the evolution and pathogenesis of H. pylori. Here we report two complete genome sequences of H. pylori phages KHP30 and KHP40, which were released spontaneously from the most pathogenic East Asian-type isolates from Japanese patients.
Keywords:
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