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Molecular mechanisms for Drosophila neuronetwork formation
Authors:Furrer Marie-Pierre  Chiba Akira
Affiliation:Department of Cell and Structural Biology, University of Illinois, Urbana, Ill. 61801, USA. mfurrer@uiuc.edu
Abstract:Understanding the establishment of functional neuronetworks is one of the frontiers of developmental neurobiology. The use of axons and dendrites from Drosophila nervous system as a model allows the identification of molecular mechanisms which give neurons the ability to guide their processes en route to connect precisely with their partners. By focusing on selected Drosophila model systems, we discuss the recent advances in our understanding of the molecular mechanisms regulating guidance, branching and targeting of axons and dendrites required for the establishment of a functional neuronetwork.
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