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Enzymatic synthesis of 2'-deoxynucleoside diphosphates and triphosphates
Authors:Suresh Pal  Vasu Nair
Affiliation:(1) Department of Chemistry, The University of Iowa, Iowa City, Iowa, USA
Abstract:2'-Deoxynucleoside diphosphates and triphosphates were synthesized from 2'-deoxy-nucleoside monophosphates by using nucleoside monophosphate kinase and nucleoside diphosphate kinase enzymes. This biocatalytic procedure is superior to chemical methods for obtaining these compounds and can be extended to other applications. © Rapid Science Ltd. 1998
Keywords:synthesis  kinases  nucleotides  diphosphates  triphosphates
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