On the nature of thumbs |
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| Authors: | Günter P Wagner Alexander O Vargas |
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| Affiliation: | Department of Ecology and Evolutionary Biology, Yale University, Prospect Street, New Haven, CT 06520-8106, USA. gunter.wagner@yale.edu |
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| Abstract: | Asymmetric regulation of Hox gene expression pre-dates the appearance of tetrapod digits, and was co-opted in the development of 'thumbness'. This asymmetric expression correlates with independent morphological evolutionary variation of digit 1. |
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