Abstract: | Microwave‐assisted extraction was employed to extract polyphenols from the leaf of Magnolia kwangsiensis Figlar & Noot . The yield of polyphenols was 2.44±0.02 % under the optimal conditions of RSM: acetone concentration of 70 %, ratio of solvent to material of 21 mL?g?1 and extraction time of 16 min. The antioxidant activities were evaluated in terms of total antioxidant ability, reducing power, DPPH ? and ? OH scavenging activity. Results showed the polyphenols presented potential antioxidant activities, especially the stronger scavenging activity on ? OH. In term of ? OH scavenging activity, the IC50 value of NKA‐9 purification was 0.335 mg mL?1, equivalent to 35.23 % of VC. The IC50 values of crude extract and ethyl acetate extract were 0.580 and 0.828 mg mL?1, equivalent to 60.99 % and 87.07 % of VC. Results indicated that M. kwangsiensis leaf polyphenols present potential antioxidant activities that make it beneficial for human health by preventing or reducing oxidative damage. |