Three biologically active heliangolides from Helianthus annuus |
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| Authors: | Otmar Spring Klaus Albert Achim Hager |
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| Affiliation: | 1. Institut für Organische Chemie, Universität Tübingen, Auf der Morgenstelle, D-7400 Tübingen, West Germany |
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| Abstract: | Growth inhibiting substances in Helianthus annuus have been investigated. From the ethanolic extract a new germacranolide with an α-methylene-γ-lactone moiety, the heliangolide niveusin B and its ethoxy derivative were isolated and their structures elucidated by spectroscopic methods. The biological activity of each was determined by inhibition in Avena coleoptile tests and antimicrobial tests. |
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| Keywords: | Compositae sesquiterpene lactones germacranolides heliangolides biological activities. |
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